Abstract

Objective: Aim of study was to describe the clinical characteristics and short-term survival of adult patients diagnosed with skeletal Ewing sarcoma.

Methods: This descriptive study included 15 patients who underwent surgical treatment after being diagnosed with skeletal Ewing sarcoma and received perioperative treatment between January 2017 and February 2023. Patients were retrospectively evaluated for tumor recurrence, metastasis development, and survival.

Results: Of the 15 patients, 10 were men and 5 were women. At the time of diagnosis, 11 (73.33%) patients were found to be non-metastatic. Bone marrow transplantation was performed in 12 (80%) patients. Metastasis was detected during the follow-up period in 6 (40%) patients. Local recurrence developed in 10 (66.7%) patients, and additional surgeries were planned due to recurrence in 5 (33.3%). Second recurrence developed in 4 (26.67%) patients and 2 (13.3%) patients who required additional surgery. Overall, survival after surgical treatment was 4 years in 11 (73.33%) patients.

Conclusion: Treatment protocols applied to adult patients with Ewing sarcoma are often adapted from pediatric clinical studies or have been developed based on the experiences of the centers. Therefore, to achieve better outcomes, it is crucial to report the treatment protocols and patient outcomes of centers providing care for adult Ewing sarcoma patients and contribute these findings to the literature in order to develop an optimal treatment strategy.