Abstract

Objective: The aim of this study was to evaluate change of Salmonella infections and antibiotic resistance of patterns in the last 10 years in a tertiary pediatric carecenter in Turkey.

Method: In this cross-sectional t study, pediatric patients under 18 years old with complaints of fever and/or acute gastroenteritis and culture positivity of Salmonella spps between January 2009 and July 2019 were included.Clinical characteristics, antibiotic susceptibility tests were recorded.

Results: Totally 136 patients,68 (50%) male with a median age of 48.5 months (4-191) were included. Thirteen (9.6%) Salmonella spps were isolated from patients under 1 year old, eighty five (62.5%) under 5 years-old, fifty one (37.5%) above 5 years old of age.Salmonella spps were isolated from stool culture (n=128,94.1%),from urine culture (n=5, 3.7%), 3 (2.2%) from blood culture. Fifty (36.8%) Salmonella spps were isolated between years of 2008-2013, eighty six (63.2%) between years of 2014-2019. The most commonly isolated serogroup was serotype A (25.7%), and serogroup B (3.7%), serogroup C (0.7%) and serogroup D (1.5%) respectively.Antibiotic resistance of Salmonella spps were as follows ampicillin (15.4%), trimethoprim sulfamethaxazole (5.1%), ciprofloxacin (3.7%), cefotaxim (2.2%),ceftriaxone (1.5%),levofloxacine (0.7%) respectively.

Conclusions: Increase in cases with Salmonella spp in the last 5 years was noticed. Salmonella infection must be kept in mind in case of acute gastroenteritis, especially in mucous and bloody cases, in children.