Forbes J Med. 2023; 4(3): 242-249 | DOI: 10.4274/forbes.galenos.2023.16046

Effectiveness of Blood Urea Nitrogen to Albumin Ratio and C-reactive Protein to Albumin Ratio in Prediction of Medical Treatment Failure for Tuboovarian Abscess

Onur YAVUZ, Sefa KURT, Aslý AKDÖNER, Kadir Alper MANKAN, Onur ADA
Dokuz Eylül University Faculty of Medicine, Department of Obstetrics and Gynecology, Ýzmir, Türkiye

Objective: This study aimed to compare the clinical characteristics of patients with tuboovarian abscess who responded to medical treatment (MT) and those who underwent surgical intervention (SI) because of MT failure.
Methods: Patients who were cured by MT were defined as Group 1 (n=25, 55.6%) and patients requiring SI were defined as Group 2 (n=20, 44.4%). The largest diameter of the abscess (cm) detected by ultrasound was recorded. Blood urea nitrogen to albumin (A) ratio (BAR) and C-reactive protein (CRP) to albumin (A) ratio (CAR) calculated according to laboratory tests on the first day of hospitalization.
Results: BAR and CAR were analyzed higher in Group 2 (p=0.3; p=0.5, respectively). The abscess size of Group 2 was statistically significantly higher than that of Group 1 (p=0.002). Abscess size greater than 5.8 cm was calculated as the cut-off point indicating failure of MT (p=0.003). The cut-off points of BAR 2.7 (p=0.3) and CAR 35.6 (p=0.09) were indicators of SI. According to the univariate and multivariate analyses, abscess size was an independent factor for predicting SI (p=0.01; p=0.03, respectively).
Conclusion: Our study suggested that BAR and CAR may be used to predict candidates for SI. Future prospective controlled studies are required to confirm our findings.

Keywords: Blood urea nitrogen to albumin ratio, C-reactive protein to albumin ratio, surgical intervention, tuboovarian abscess

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Tubaovaryan Abselerin Medikal Tedavisinin Baþarýsýzlýðýnýn Tahmininde Kan Üre Azotu/Albümin Oraný ve C-reaktif Protein/Albümin Oranýnýn Etkinliðinin Deðerlendirilmesi

Onur YAVUZ, Sefa KURT, Aslý AKDÖNER, Kadir Alper MANKAN, Onur ADA
Dokuz Eylül Üniversitesi Týp Fakültesi, Kadýn Hastalýklarý ve Doðum Anabilim Dalý, Ýzmir,Türkiye

Amaç: Bu çalýþmanýn amacý, medikal tedaviye (MT) yanýt veren tubaovaryan abse (TOA) hastalarý ile MT'nin baþarýsýzlýðý nedeniyle cerrahi giriþim (SI) uygulanan hastalarýn klinik özelliklerini karþýlaþtýrmaktýr.
Yöntem: MT ile iyileþen hastalar Grup 1 (n=25, %55,6) ve cerrahi giriþim gerektiren hastalar Grup 2 (n=20, %44,4) olarak tanýmlandý. Absenin ultrason ile saptanan en büyük çapý (cm) kaydedildi. Kan üre azotu/albümin (A) oraný (BAR) ve C-reaktif protein (CRP)/albümin (A) oraný (CAR) hastaneye yatýþýn ilk günündeki laboratuvar testlerine göre hesaplandý.
Bulgular: BAR ve CAR, Grup 2'de daha yüksek olarak analiz edildi (p=0,3; p=0,5, sýrasýyla). Grup 2'nin abse boyutu Grup 1'e göre istatistiksel olarak anlamlý derecede yüksekti (p=0,002). 5,8 cm'den büyük abse boyutu, MT baþarýsýzlýðýný gösteren kesme noktasý olarak hesaplandý (p=0,003). BAR 2,7 (p=0,3) ve CAR 35,6 (p=0,09) kesme noktalarý cerrahi giriþim gerektiren grubun göstergesiydi. Tek deðiþkenli ve çok deðiþkenli analize göre abse boyutu cerrahi giriþim gerektirmeyi öngörmede baðýmsýz faktör olarak saptandý (p=0,01; p=0,03, sýrasýyla).
Sonuç: Çalýþmamýz, BAR ve CAR'nin SI gerektiren TOA hastalarýný tahmin etmede kullanýlabileceðini düþündürmektedir. Bulgularýmýzý doðrulamak için prospektif kontrollü çalýþmalara ihtiyaç vardýr.

Anahtar Kelimeler: Kan üre azotu/albümin oraný, C-reaktif protein/albumin oraný, cerrahi müdahale, tubaovaryan abse

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