Forbes J Med. 2020; 1(2): 36-41 | DOI: 10.5222/forbes.2020.58066

Computed Tomography and Magnetic Resonance Assessment of Choroid Plexus Xanthogranulomas

Sedat Altay
Izmir Katip Celebi U. Ataturk Research And Training Hospital, Department Of Radiology, Izmir

INTRODUCTION: Seventy-five adult patients with retrospectively detected incidental choroid plexus xanthogranulomas (CPX) were evaluated with non-contrast brain computed tomography (CT) and contrast-enhanced brain magnetic resonance imaging (MRI) images. In this study, we aim to determine the imaging properties of CPX with CT and MRI, to evaluate the difference between white matter and CPX with diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC), and ensure its potential use in the follow-up and treatment of CPX patients.
METHODS: In this study, lesions between 5-25 mm were evaluated. CPX and white matter ADC measurements were performed on CT and MRI images in all lesions. An independent sample t-test was used for statistics. Cases with a history of cranial operation and any malignancy were excluded due to the possibility of metastasis.
RESULTS: Bilateral CPX was detected in 41 and unilateral CPX in 34 patients. On CT, bilateral CPX calcifications were observed in 21 and unilateral calcifications in 44 patients. Calcification was not observed in brain CT in 10 patients. ADC (apparent diffusion coefficients) measurement was made from the widest and non-calcific parts of all lesions. ADC measurements were between 1.33-1.69x10-3/mm2/s and the mean value was 1.48x10-3/mm2/s. In all cases, the ADC value was lower relative to the white matter. ADC value was found to be higher and closer to the white matter ADC values than cases with a homogenous appearance in CPX patients with heterogeneous internal structure.
DISCUSSION AND CONCLUSION: ADC value is useful in the diagnosis of CPX. In conclusion, the follow-up of the ADC value is useful in the diagnosis and follow-up of CPX.

Keywords: Choroid Plexus Xanthogranulomas (CPX), Computed Tomography, Diffusion Magnetic Resonance(DWI), Apparent Diffusion Coefficient (ADC)

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Koroid Pleksus Ksantogranülomu: Bilgisayarlý Tomografi ve Manyetik Rezonans Görüntüleme Bulgularý

Sedat Altay
Ýzmir Katip Çelebi Ü.Atatürk Eðitim ve Araþtýrma Hastanesi, Radyoloji Departmaný Ýzmir.

GÝRÝÞ ve AMAÇ: Geriye dönük, rastlantýsal olarak, koroid pleksus ksantogranülomu (KPK) saptanan 75 eriþkin hasta kontrastsýz beyin bilgisayarlý tomografi (BT) ve kontrastlý beyin manyetik rezonans (MRG) görüntüleri ile deðerlendirilmiþtir. Bu çalýþmada amacýmýz, KPK’nýn görüntüleme özelliklerinin BT ve MRG ile belirlenmesi, difüzyon aðýrlýklý görüntüleme (DAG) ve görünür difüzyon katsayýsý (GDK) ile beyaz cevher ile KPK arasýndaki farký deðerlendirip, KPK hastalarýnýn takip ve tedavinin izleminde kullanýlabilmesini saðlamaktýr.
YÖNTEM ve GEREÇLER: Bu çalýþmada, 5-25 mm arasý lezyonlar deðerlendirildi. Tüm lezyonlarda BT ve MR görüntülerinde KPK ve beyaz cevher GDK ölçümleri yapýldý. Ýstatistik için baðýmsýz örneklem t testi kullanýldý. Kraniyal operasyon ve herhangi bir malignite öyküsü olan olgular metastaz olasýlýðý nedeniyle çalýþma dýþý býrakýldý.
BULGULAR: Kýrk bir hastada iki taraflý, 34 hastada tek taraflý KPK saptandý. BT de, 21 hastada iki taraflý, 44 hastada tek taraflý KPK kalsifikasyonlarý izlendi. On hastada beyin BT de kalsifikasyon izlenmedi. Tüm lezyonlarýn en geniþ ve kalsifik olmayan kýsýmlarýndan GDK ölçümü yapýldý. GDK 1,33-1,69x10-3 mm2/s, ortalama deðeri 1,48x10-3 mm2/s bulundu. Tüm olgularda GDK deðeri beyaz cevherden düþük bulundu. Heterojen iç yapýdaki KPK izlenen olgularda GDK deðeri, homojen görünümdeki olgulara göre, yüksek ve beyaz cevhere daha yakýn bulundu.
TARTIÞMA ve SONUÇ: KPK tanýsýnda GDK deðeri tanýda yararlýdýr. Sonuç olarak, GDK deðeri takibi koroid pleksus kistleri taný ve takibinde yararlýdýr.

Anahtar Kelimeler: Koroid Pleksus Ksantogranülomu, Bilgisayarlý Tomografi, Diffüzyon Manyetik Rezonans Görüntüleme, Görünür Difüzyon Katsayýsý (GDK)

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