Measuring and Evaluating the Adherence to and Effectiveness of Formula Milk Use in Healthy Infants in Türkiye

�ZDENER, Fatih; KILI�, �lknur; SAF, Co�kun; DEM�RCAN B�LEN, Tu�ba; �EL�K, Dicle; URA�, Nurdan; G�L, Doruk; DEM�REL, Gamze; TEMEL, Hayrettin; �OBAN, Dilek; G�LCAN, ENVER MAHIR; S�RSAL, Alihan; ERTEK�N, Vildan; SEL�MO�LU, Mukadder Ay�e

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Measuring and Evaluating the Adherence to and Effectiveness of Formula Milk Use in Healthy Infants in Türkiye [Forbes J Med]

Forbes J Med. 2023; 4(3): 336-345 | DOI: 10.4274/forbes.galenos.2023.30306

Measuring and Evaluating the Adherence to and Effectiveness of Formula Milk Use in Healthy Infants in Türkiye

Fatih �ZDENER¹, �lknur KILI�², Co�kun SAF², Tu�ba DEM�RCAN B�LEN², Dicle �EL�K³, Nurdan URA�⁴, Doruk G�L⁴, Gamze DEM�REL⁵, Hayrettin TEMEL⁵, Dilek �OBAN⁶, ENVER MAHIR G�LCAN⁶, Alihan S�RSAL⁷, Vildan ERTEK�N⁶, Mukadder Ay�e SEL�MO�LU⁸
¹Bahcesehir University Faculty of Medicine, Department of Pharmacology
²Ata�ehir Florance Nightingale Hospital, Department of Pediatric Health and Diseases
³Sisli Memorial Hospital, Department of Pediatric Health and Diseases
⁴Istinye University Bahcesehir Liv Hospital, Department of Pediatric Health and Diseases
⁵Mega Medipol University Hospital, Department of Pediatric Health and Diseases
⁶Ac�badem University Faculty of Medicine Hospital, Department of Pediatric Health and Diseases and Pediatric Gastroenterology
⁷Bahcesehir University Faculty of Medicine, Department of Neuroscience
⁸Atasehir Memorial Hospital, Department of Pediatric Gastroenterology

Objective: Formula milk aims to mimic breast milk or can serve as a complementary diet, thus reducing the risk of developing nutritional deficiencies. In this study, we evaluated the factors affecting compliance with the use of prebiotic formula milk with a galacto-oligosaccharides/fructo-oligosaccharides ratio of 9: 1.
Methods: The study included 63 healthy girls and 58 healthy boys who consumed formula milk for 4-12 months. A brief survey was conducted among the parents of these children at the end of the first and third months. Height, weight for age, and weight for height z-scores were compared between the first and follow-up visits. Perceived symptoms, frequency of infections, complementary food intake, and frequency of stool movements were also discussed.
Results: The anthropometrics significantly increased over the three months. Intolerability negatively affected compliance with formula use (p<0.001). The infection rate decreased in 13.3% of the infants, and 65.3% experienced no change in complementary food intake. The parent's opinion about the benefits of formula milk, the parent's forgetfulness, and the thought that formula milk reduces the intake of complementary foods were the factors that negatively affected compliance with formula milk use. The mothers of infants who were introduced to a complementary diet <17 weeks were 2.4 years younger (p=0.006).
Conclusion: Parents should be educated regarding the benefits of formula milk. Formula milk used led to an anthropometrical z-score increase and a significant decrease in the rate of infection, which should be emphasized to the parents to maximize compliance.

Keywords: Formula milk, adherence, nutritional deficiency, growth

Türkiye'deki Sa�l�kl� Bebeklerde Formül Süt Kullan�m�na Uyum ve Etkinli�in �l�ülmesi ve De�erlendirilmesi

Fatih �ZDENER¹, �lknur KILI�², Co�kun SAF², Tu�ba DEM�RCAN B�LEN², Dicle �EL�K³, Nurdan URA�⁴, Doruk G�L⁴, Gamze DEM�REL⁵, Hayrettin TEMEL⁵, Dilek �OBAN⁶, ENVER MAHIR G�LCAN⁶, Alihan S�RSAL⁷, Vildan ERTEK�N⁶, Mukadder Ay�e SEL�MO�LU⁸
¹Bah�e�ehir University Faculty of Medicine, Department of Pharmacology, �stanbul, Türkiye
²Ata�ehir Florence Nightingale Hospital, Clinic of Pediatric Health and Diseases, �stanbul, Türkiye
³�i�li Memorial Hospital, Clinic of Pediatric Health and Diseases, �stanbul, Türkiye
⁴�stinye University, Bah�e�ehir Liv Hospital, Clinic of Pediatric Health and Diseases, �stanbul, Türkiye
⁵Mega Medipol University Faculty of Medicine, Department of Pediatric Health and Diseases, �stanbul, Türkiye
⁶Ac�badem University Faculty of Medicine Hospital, Department of Pediatric Health and Diseases and Pediatric Gastroenterology, �stanbul, Türkiye
⁷Bah�e�ehir University Faculty of Medicine, Department of Neuroscience, �stanbul, Türkiye
⁸Ata�ehir Memorial Hastanesi, �ocuk Gastroenteroloji Anabilim Dal�

Ama�: Formül süt, anne sütünü taklit etmeyi ama�lar veya tamamlay�c� bir diyet olarak hizmet edebilir, bu nedenle beslenme bozuklu�unun geli�me riskini azalt�r. Bu �al��mada, galakto-oligosakkaritler/frukto-oligosakkaritler oran� 9: 1 olan prebiyotik formül süt kullan�m�yla ilgili uyumu etkileyen fakt�rleri de�erlendirmeyi ama�lad�k.
Y�ntem: �al��ma, 4-12 ay boyunca formül süt tüketen 63 sa�l�kl� k�z ve 58 sa�l�kl� erkek �ocu�u i�eriyordu. Bu �ocuklar�n ebeveynleri aras�nda ilk ve ü�üncü ay�n sonunda k�sa bir anket yap�ld�. �lk ve takip ziyaretleri aras�nda boy, kilo ya�a g�re ve boy kilo i�in z puanlar� kar��la�t�r�ld�. Semptomlar, enfeksiyon s�kl��, tamamlay�c� g�da al�m� ve d��k�lama s�kl�� da tart��ld�.
Bulgular: Antropometrik �l�ümler ü� ay boyunca �nemli �l�üde artt�. Tahammülsüzlük, formül kullan�m�na uyumu olumsuz etkiledi (p<0,001). Bebeklerin %13,3'ünde enfeksiyon oran� azald� ve %65,3'ünde tamamlay�c� g�da al�m�nda de�i�iklik olmad�. Ebeveynlerin formül sütün faydalar� hakk�ndaki dü�ünceleri, ebeveynlerin unutkanl�� ve formül sütün tamamlay�c� g�da al�m�n� azaltt�� dü�üncesi, formül süt kullan�m�na uyumu olumsuz etkileyen fakt�rlerdi. Tamamlay�c� bir diyete <17 hafta i�inde ba�lat�lan bebeklerin anneleri 2,4 ya� daha gen�ti (p=0,006).
Sonu�: Ebeveynler, formül sütün faydalar� hakk�nda e�itilmelidir. Formül süt kullan�m�, antropometrik z puanlar�nda bir art��a ve enfeksiyon oran�nda �nemli bir azalmaya yol a�m��t�r, bu nedenle ebeveynlere uyumu maksimuma ��karmak i�in bu durum vurgulanmal�d�r.

Anahtar Kelimeler: Formü, l süt, ba�l�l�k, beslenme yetersizli�i, büyüme

Corresponding Author: Fatih �ZDENER, T�rkiye
Manuscript Language: English

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