Forbes J Med. 2021; 2(1): 49-53 | DOI: 10.5222/forbes.2021.66376

Castleman’s Disease: Due to a Rare Intraabdominal Location

Mehmet Cihan Karacaoðlu¹, Nursel Yurttutan¹, Betül Kýzýldað¹, Turgay Kara¹, Sezen Koçarslan^2
1Kahramanmaraþ Sütçüimam Univesity, Department of Radiology
²Kahramanmaraþ Sütçüimam Univesity, Department of Pathology

Castleman disease (CD) is a rare benign disease with unknown etiology. It is also called angiofollicular lymph node hyperplasia, giant lymph node hyperplasia, lymph node hamartoma, benign giant lymphoma. Histologically, it is classified as hyaline vascular and plasma cell variant, but rarely features of two types can coexist. Most of the cases with unisentric disease are hyaline vascular and most of the cases with multicentric disease are in plasma cell histological type. Although it is frequently located in thorax, it can be found throughout the body. Salivary glands, lungs, pancreas, larynx, parotid gland, meninges, and even limb muscles can be affected as extralymphatic spread. Since it is localized in the middle and anterior mediastinum in the thorax, it should be differentiated from mediastinal autoimmune and neoplastic diseases. In this case report, we aimed to present the radiological findings of a CD case with a rare intraabdominal location.

Keywords: Castleman Disease, computed tomography, lymph nodes, lymphoma

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Castleman Hastalýðý: Nadir Intraabdominal Yerleþim Nedeniyle

Mehmet Cihan Karacaoðlu¹, Nursel Yurttutan¹, Betül Kýzýldað¹, Turgay Kara¹, Sezen Koçarslan^2
1Kahramanmaraþ Sütçüimam Üniversitesi, Radyoloji AD
²Kahramanmaraþ Sütçüimam Üniversitesi, Patoloji AD

Castleman hastalýðý (CH), etiyolojisi tam olarak bilinmeyen ve nadir görülen benign bir hastalýktýr. Anjiyofoliküler lenf nodu hiperplazisi, dev lenf nodu hiperplazisi, lenf nodu hamartomu, benign giant lenfoma olarak da adlandýrýlýr. Histolojik olarak hyalin vasküler ve plazma hücreli varyant olarak sýnýflandýrýlýr ancak nadiren iki tipe ait özellikler bir arada bulunabilir. Unisentrik hastalýðý olan olgularýn çoðu hyalin vasküler, multisentrik hastalýðý olan olgularýn çoðu ise plazma hücreli histolojik tipindedir.
Sýklýkla toraksta yerleþim göstermekle beraber tüm vücutta bulunabilir. Tükrük bezleri, akciðer, pankreas, larinks, parotis bezi, meninksler hatta ekstremite kaslarý ekstralenfatik olarak tutulabilir. Toraksta genellikle orta ve ön mediastende lokalizedir. Mediastinal otoimmün ve neoplastik hastalýklardan ayýrt edilmesi gerekir. Burada, nadir bir yerleþim yeri olan intraabdominal yerleþimli CH olgusunun radyolojik bulgularýnýn sunulmasý amaçlandý.

Anahtar Kelimeler: Casteman Hastalýðý, bilgisayarlý tomografi, lenf nodlarý, lenfoma

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